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Research Article| Volume 4, ISSUE 2, P182-187, April 2018

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Burden of disease due to sleep duration and sleep problems in the elderly

Published:January 15, 2018DOI:https://doi.org/10.1016/j.sleh.2017.11.007

      Abstract

      Objectives

      The Centers for Disease Control and Prevention emphasizes conceptualizing sleep as a healthy behavior. Although a large literature exists documenting the morbidity or mortality of suboptimal sleep, fewer investigations have examined the burden of disease in a single number combining morbidity and mortality. This study examined the morbidity, as measured by health-related quality of life (HRQOL), mortality, and quality-adjusted life years (QALY) due to suboptimal (inadequate or excessive) sleep.

      Design and participants

      We ascertained respondents' HRQOL scores and mortality status from the 2005 to 2008 National Health and Nutrition Examination Survey (NHANES) with mortality follow-up data through December 31, 2011 for respondents aged 65 and older (n = 2380). We estimated mean QALY according to duration of sleep, minutes to fall asleep, number of sleeping problems, and daytime impact.

      Results

      More than one third of participants reported a suboptimal sleep duration. Short sleep duration had a greater adverse impact on morbidity, with reductions in HRQOL, while long sleep duration had a greater adverse impact on mortality. Compared to participants who reported between 7 and 9 hours of sleep per night, mean QALYs were significantly lower among participants who slept 10 or more hours a night (7.8 QALY; decrease of 9.8 QALY).

      Conclusions

      This study confirmed the association between suboptimal sleep and greater burden of disease among the elderly US population. Our findings provide support for treating sleep as a healthy (health risk) behavior, thereby having implications for primary care providers and public health surveillance.

      Keywords

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      References

        • Ford E.S.
        • Cunningham T.J.
        • Croft J.B.
        Trends in self-reported sleep duration among US adults from 1985–2012.
        Sleep. 2015; 38: 829-832
        • Centers for Disease Control and Prevention (CDC)
        Insufficient sleep is a public health problem.
        (Available at)
        https://www.cdc.gov/features/dssleep/
        Date accessed: August 6, 2017
        • Perry G.S.
        • Patil S.P.
        • Presley-Cantrell L.R.
        Raising awareness of sleep as a healthy behavior.
        Prev Chronic Dis. 2013; 10: 130081
      1. Healthy People 2020 [Internet]. Washington, DC: U.S. Department of Health and Human Services, Office of Disease Prevention and Health Promotion. [Available at https://www.healthypeople.gov/2020/topics-objectives/topic/sleep-health/objectives; accessed on 7 June 2017].

        • Watson N.F.
        • Badr M.S.
        • Belenky G.
        • et al.
        Joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society on the recommended amount of sleep for a healthy adult: methodology and discussion.
        Sleep. 2015; 38: 1161-1183
        • Hirshkowitz M.
        • Whiton K.
        • Albert S.M.
        • et al.
        National Sleep Foundation's updated sleep duration recommendations: final report.
        Sleep Health. 2015; 1: 233-243
        • da Silva A.A.
        • de Mello R.G.
        • Schaan C.W.
        • Fuchs F.D.
        • Redline S.
        • Fuchs S.C.
        Sleep duration and mortality in the elderly: a systematic review with meta-analysis.
        BMJ Open. 2016; 6: e008119
        • Cappuccio F.P.
        • D'Elia L.
        • Strazzullo P.
        • Miller M.A.
        Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies.
        Sleep. 2010; 33: 585-592
        • Gallicchio L.
        • Kalesan B.
        Sleep duration and mortality: a systematic review and meta-analysis.
        J Sleep Res. 2009; 18: 148-158
        • Faubel R.
        • Lopez-Garcia E.
        • Guallar-Castillón P.
        • Balboa-Castillo T.
        • Gutiérrez-Fisac J.L.
        • Banegas J.R.
        • Rodríguez-Artalejo F.
        Sleep duration and health-related quality of life among older adults: a population-based cohort in Spain.
        Sleep. 2009; 32: 1059-1068
        • Hossin M.Z.
        From habitual sleep hours to morbidity and mortality: existing evidence, potential mechanisms, and future agenda.
        Sleep Health. 2016; 2: 146-153
        • Devore E.E.
        • Grodstein F.
        • Duffy J.F.
        • Stampfer M.J.
        • Czeisler C.A.
        • Schernhammer E.S.
        Sleep duration in midlife and later life in relation to cognition.
        J Am Geriatr Soc. 2014; 62: 1073-1081
        • Yang X.
        • Chen H.
        • Li S.
        • Pan L.
        • Jia C.
        Association of sleep duration with the morbidity and mortality of coronary artery disease: a meta-analysis of prospective studies.
        Heart Lung Circ. 2015; 24: 1180-1190
        • Zhai L.
        • Zhang H.
        • Zhang D.
        Sleep duration and depression among adults: a meta-analysis of prospective studies.
        Depress Anxiety. 2015; 32: 664-670
        • Empana J.P.
        • Dauvilliers Y.
        • Dartigues J.F.
        • et al.
        Excessive daytime sleepiness is an independent risk indicator for cardiovascular mortality in community-dwelling elderly: the three city study.
        Stroke. 2009; 40: 1219-1224
        • Gómez-Olivé F.X.
        • Thorogood M.
        • Kandala N.B.
        • Tigbe W.
        • Kahn K.
        • Tollman S.
        • Stranges S.
        Sleep problems and mortality in rural South Africa: novel evidence from a low-resource setting.
        Sleep Med. 2014; 15: 56-63
        • Boden-Albala B.
        • Roberts E.T.
        • Bazil C.
        • et al.
        Daytime sleepiness and risk of stroke and vascular disease: findings from the Northern Manhattan Study (NOMAS).
        Circ Cardiovasc Qual Outcomes. 2012; 5: 500-507
        • National Academies of Science, Engineering, and Medicine
        The Growing Gap in Life Expectancy by Income: Implications for Federal Programs and Policy Responses.
        The National Academies Press, Washington, DC2015
        • Liu Y.
        • Wheaton A.G.
        • Chapman D.P.
        • Croft J.B.
        Sleep duration and chronic diseases among US adults age 45 years and older: evidence from the 2010 Behavioral Risk Factor Surveillance System.
        Sleep. 2013; 36: 1421-1427
        • Zdanys K.F.
        • Steffens D.C.
        Sleep disturbances in the elderly.
        Psychiatr Clin N Am. 2015; 38: 723-741
        • Ensrud K.E.
        • Blackwell T.L.
        • Redline S.
        • Ancoli-Israel S.
        • Paudel M.L.
        • et al.
        Sleep disturbances and frailty status in older community-dwelling men.
        J Am Geriatr Soc. 2009; 57: 2085-2093
        • Stone K.L.
        • Blackwell T.L.
        • Ancoli-Israel S.
        • et al.
        Sleep disturbances and risk of falls in older community-dwelling men: the outcomes of Sleep Disorders in Older Men (MrOS sleep) study.
        J Am Geriatr Soc. 2014; 62: 299-305
        • Stone K.L.
        • Ancoli-Israel S.
        • Blackwell T.
        • et al.
        Actigraphy-measured sleep characteristics and risk of falls in older women.
        Arch Intern Med. 2008; 168: 1768-1775
        • Spoelstra S.L.
        • Given B.
        • You M.
        • Given C.W.
        The contribution falls have to increasing risk of nursing home placement in community-dwelling older adults.
        Clin Nurs Res. 2012; 21: 24-42
        • Grandner M.A.
        • Drummond S.P.
        Who are the long sleepers? Towards an understanding of the mortality relationship.
        Sleep Med Rev. 2007; 11: 341-360
      2. Gold M.R. Siegel J.E. Russell L.B. Weinstein M.C. Cost-Effectiveness in Health and Medicine. Oxford University Press, New York1996
        • Brown D.S.
        • Jia H.
        • Zack M.M.
        • Thompson W.W.
        • Haddix A.C.
        • Kaplan R.M.
        Using health-related quality of life and quality-adjusted life expectancy for effective public health surveillance and prevention.
        Expert Rev Pharmacoecon Outcomes Res. 2013; 13: 425-427
        • Centers for Disease Control and Prevention (CDC)
        • National Center for Health Statistics (NCHS)
        National Health and Nutrition Examination Survey Data.
        U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Hyattsville, MD2005–2006 ([Available at http://wwwn.cdc.gov/nchs/nhanes/search/nhanes05_06.aspx; accessed on 6 June 2017])
        • Centers for Disease Control and Prevention (CDC)
        • National Center for Health Statistics (NCHS)
        NCHS Data Linked to Mortality Files.
        U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Hyattsville, MD2011 ([Available at http://www.cdc.gov/nchs/data_access/data_linkage/mortality.htm; accessed on 6 June 2017])
        • Centers for Disease Control and Prevention
        Measuring Healthy Days: Population Assessment of Health-Related Quality of Life.
        U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Division of Adult and Community Health, 2000 ([Available at http://www.cdc.gov/hrqol/pdfs/mhd.pdf; accessed on 8 June 2017])
        • Jia H.
        • Lubetkin E.I.
        Estimating EuroQol EQ-5D scores from population Healthy Days data.
        Med Decis Making. 2008; 28: 491-499
        • Jia H.
        • Zack M.M.
        • Moriarty D.G.
        • Fryback D.G.
        Predicting the EuroQol Group's EQ-5D index from CDC's “Healthy Days” in a US sample.
        Med Decis Making. 2011; 31: 174-185
        • Gold M.R.
        • Stevenson D.
        • Fryback D.G.
        HALYS and QALYS and DALYS, Oh My: similarities and differences in summary measures of population health.
        Annu Rev Public Health. 2002; 23: 115-134
        • National Research Council
        Accounting for Health and Health Care: Approaches to Measuring the Sources and Costs of their Improvement.
        in: Panel to Advance a Research Program on the Design of National Health Accounts, Committee on National Statistics, Division of Behavioral and Social Sciences and Education. The National Academies Press, Washington, DC2010
        • Loprinzi P.D.
        • Joyner C.
        Meeting sleep guidelines is associated with better health-related quality of life and reduced premature all-cause mortality risk.
        Am J Health Promot. 2018; 32: 68-71
        • Centers for Disease Control and Prevention
        Fact sheets - alcohol use and your health.
        (Available at)
        • WHO
        Physical Status: The Use and Interpretation of Anthropometry: Report of a World Health Organization (WHO) Expert Committee.
        World Health Organization, Geneva, Switzerland1995
        • Centers for Disease Control and Prevention (CDC)
        • National Center for Health Statistics (NCHS)
        National Health and Nutrition Examination Survey Data.
        U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Hyattsville, MD2005–2006 (Accessed 11 October 2017)
        • Kroenke K.
        • Strine T.W.
        • Spitzer R.L.
        • Williams J.B.
        • Berry J.T.
        • Mokdad A.H.
        The PHQ-8 as a measure of current depression in the general population.
        J Affect Disord. 2009; 114: 163-173
        • Jia H.
        • Lubetkin E.I.
        Impact of nine chronic conditions for US adults aged 65 and older: an application of a hybrid estimator of quality-adjusted life years throughout remainder of lifetime.
        Qual Life Res. 2016; 25: 1921-1929
        • Shankar A.
        • Chaumathi S.
        • Kalidindi S.
        Sleep duration and self-rated health: the National Health Interview Survey 2008.
        Sleep. 2011; 34: 1173-1177
        • Léger D.
        • Poursain B.
        • Neubauer D.
        • Uchiyama U.
        An international survey of sleeping problems in the general population.
        Curr Med Res Opin. 2008; 24: 307-317
        • Foley D.J.
        • Monjan A.A.
        • Brown S.L.
        • Simonsick E.M.
        • Wallace R.B.
        • Blazer D.G.
        Sleep complaints among elderly persons: an epidemiologic study of three communities.
        Sleep. 1995; 18: 425-432
        • Smagula S.F.
        • Stone K.L.
        • Fabio A.
        • Cauley J.A.
        Risk factors for sleep disturbances in older adults: evidence from prospective studies.
        Sleep Med Rev. 2016; 25: 21-30
        • Jia H.
        • Lubetkin E.I.
        Dose-response effect of smoking status on quality-adjusted life years among U.S. adults aged 65 years and older.
        J Public Health (Oxf). 2016; ([Epub ahead of print])
        • Institute of Medicine
        Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem.
        The National Academies Press, Washington, DC2006
        • Bibbins-Domingo K.
        • Grossman D.C.
        • Curry S.J.
        • et al.
        Screening for obstructive sleep apnea in adults: US Preventive Services Task Force recommendation statement.
        JAMA. 2017; 317: 407-414
        • Jungquist C.R.
        • Mund J.
        • Aquilina A.T.
        • Klingman K.
        • et al.
        Validation of the Behavioral Risk Factor Surveillance System questions.
        J Clin Sleep Med. 2016; 12: 301-310
        • Brassington G.S.
        • King A.C.
        • Bliwise D.L.
        Sleep problems as a risk factor for falls in a sample of community-dwelling adults aged 64–99 years.
        J Am Geriatr Soc. 2000; 48: 1234-1240
        • Miner B.
        • Kryger M.H.
        Sleep in the aging population.
        Sleep Med Clin. 2017; 12: 31-38
        • Bloom H.G.
        • Ahmed I.
        • Alessi C.A.
        • et al.
        Evidence-based recommendations for the assessment and management of sleep disorders in older persons.
        J Am Geriatr Soc. 2009; 57: 761-789
        • Lauderdale D.S.
        • Knutson K.L.
        • Yan L.L.
        • Liu K.
        • Rathouz P.J.
        Self-reported and measured sleep duration: how similar are they?.
        Epidemiology. 2008; 19: 838-845
        • Kurina L.M.
        • McClintock M.K.
        • Chen J.H.
        • Waite L.J.
        • Thisted R.A.
        • Lauderdale D.S.
        Sleep duration and all-cause mortality: a critical review of measurement and associations.
        Ann Epidemiol. 2013; 23: 361-370
        • Jia H.
        • Zack M.M.
        • Thompson W.W.
        • Dube S.R.
        Quality-adjusted life expectancy (QALE) loss due to smoking in the United States.
        Qual Life Res. 2013; 22: 27-35